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Lineage instructive TFs act through synergistic and cross an
2018-10-31
Lineage-instructive TFs act through synergistic and cross-antagonistic interactions, are typically able to access closed chromatin (Zaret and Carroll, 2011), preferentially target sites with specific histone mark combinations, and bind to either nucleosome-depleted or nucleosome-dense regions (Soufi
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Introduction Glioblastoma multiforme GBM is the most
2018-10-31
Introduction Glioblastoma multiforme (GBM) is the most common adult primary ionomycin tumor, with an extremely dismal prognosis and high rate of recurrence following standard therapy (Wen and Kesari, 2008). Populations of brain tumor initiating cells (BTICs), which express many of the properties o
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In the absence of SOX
2018-10-31
In the absence of SOX2+ stem cells and Notch signaling in Rbp-Jf/f, Prop1-Cre mutant mice, the pituitary glands are hypoplastic and dysmorphic. Interestingly, re-entry of PIT1+ lineages into the diprenorphine manufacturer after birth is delayed in the mutant. Consistent with our finding, reduced po
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is satisfied where k is the number
2018-10-30
is satisfied, where k is the number of the least harmonic of the canonical expansion. If we imagine an optimal canonical expansion (7), then k can be set to equal M. The inversely proportional relationship between T0 and a is in agreement with Kotelnikov’s sampling theorem [11]. Notice that the s
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br Results Table shows the characteristics of the study
2018-10-30
Results Table 1 shows the characteristics of the study participants by gender. Occupational position differed significantly by gender. Compared to women, men were more likely to be manual/service workers and professionals/managers, and were less likely to be clerks and associate-professionals. Me
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This pattern suggests that we targeted children who
2018-10-30
This pattern suggests that we targeted children who were already too old to receive maximum benefit from MNP. From Fig. 1 we notice that the studies that found MNP to be most effective at increasing haemoglobin were those with very low average initial haemoglobin (severe anaemia) and where the contr
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Many of the suggested mechanisms by which education may
2018-10-30
Many of the suggested mechanisms by which education may influence health can be argued to be most strongly operative during secondary schooling, given dramatic cognitive development during adolescence and the emergence of key health issues such as substance use, depression, sexually transmitted infe
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br Tectonomagmatic setting and metallogeny The
2018-10-30
Tectonomagmatic setting and metallogeny The Hecaokeng uranium ore field is situated approximately 100 km east-southeast of Ganzhou City, southern Jiangxi Province, Southeast China (Fig. 1). It lies in the central part of the Cathaysia Block of Proterozoic age, which is separated from the older Ya
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Informaci n proveniente del exterior
2018-10-30
Información proveniente del exterior, que examinaremos más adelante, coloca a México en un lugar importante en cuanto a la existencia en su territorio de importantes recursos prospectivos de gas natural no convencional, en particular shale gas. Con buy SCR 7 en esa información y trabajos de Pemex,
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Introducci n La desigualdad en la distribuci n funcional
2018-10-30
Introducción La desigualdad en la distribución funcional del ingreso en México ha venido acentuándose desde mediados/fines de los años setenta. Como lo analiza Samaniego (2014), la participación de los salarios en el ingreso total se redujo gradualmente en la segunda mitad de los años setenta y lue
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br La presencia de econom as de escala frecuentemente
2018-10-30
La presencia de economías de escala frecuentemente obliga nothing las empresas a producir masivamente, lo que implica que la industria sólo permita la presencia de unas cuantas empresas, debido a ello cada empresa en esa industria tiene incentivos para producir cada vez más, para reducir costos y
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br Methods br Results A total of
2018-10-30
Methods Results A total of 102 patients (69 males and 33 females, 70.1±9.2years) were registered in the study. Baseline clinical characteristics are presented in Table 1. Telomere G-tail length was negatively correlated with aging and positively correlated with total telomere length (ρ −0.287,
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Selection of the best embryo for
2018-10-30
Selection of the best conotoxin for transfer is imprecise and the current methods involve morphologic criteria (), on the belief that those with a better shape are more likely to be chromosomically normal and implant. However, many morphologically normal blastocysts are aneuploid or will not implant
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br Mathematical modeling has played
2018-10-30
Mathematical modeling has played an important role in the fight against HIV. Mathematical analysis of a protease inhibitor experiment enabled the development of the first suppressive multi-drug regimens for treating HIV (). Mathematical model use in disease epidemiology dates back almost a century
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Ten years ago Shinya Yamanaka and
2018-10-30
Ten years ago Shinya Yamanaka and colleagues from Kyoto University (Japan) described the creation of induced pluripotent stem 4-ethylphenyl sulfate (iPSCs), first from mice, then humans a year later. The ability to ‘reprogram’ mature cells into iPSCs by introducing genes that encode specific transc
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