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br Bioactive peptides on NO bioavailability
2018-11-08
Bioactive peptides on NO bioavailability and endothelial function Bioactive peptides on inflammation Bioactive peptides as RAS modulators Conclusions Acknowledgements This study was supported by Alberta Livestock and Meat Agency (ALMA) and Natural Sciences and Engineering Research Cou
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br Conclusions br Introduction Genetically
2018-11-08
Conclusions Introduction Genetically modified organisms (GMOs), also known as genetically engineered or transgenic organisms, for use as human foods or animal feeds are commonplace nowadays. On November 19, 2015, the Food and Drug Administration (FDA) of the United States approved the first-ev
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mpges-1 inhibitors Hence we propose a model in which transie
2018-11-08
Hence, we propose a model in which transient HES5 activity in early mesoderm instructs the timing of cardiac fate specification while repressing the first wave of hematopoiesis. Thus in the absence of this signal, commitment to EryP is favored by default. Moreover, after a pulse of Hes5 instructing
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While the in vivo significance of
2018-11-08
While the in vivo significance of our in vitro findings was examined in xenograft and metastasis studies, we observed a dramatic suppression of tumor growth and metastasis of SW480 CRC GSK-J1 sodium salt manufacturer by EDA silencing, which is associated with increased apoptosis and reduced expressi
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Several studies have shown a complex pattern of
2018-11-08
Several studies have shown a complex pattern of Ahr expression during early mouse embryogenesis. Fertilized eggs at the 1-cell stage show detectable levels of Ahr mRNA (Dey and Nebert, 1998; Wu et al., 2002) and high levels of AHR activity, as determined by an elevated constitutive mRNA level of the
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br Materials and methods br
2018-11-08
Materials and methods Resource table Resource details This line was derived from a 62-year-old female with familial hypertrophic cardiomyopathy (HCM). HCM is a genetic heart disease with a prevalence of up to 1 in 200 people and is characterised by unexplained hypertrophy of the left ventricl
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The following is the supplementary data related
2018-11-08
The following is the supplementary data related to this article. Author contribution Acknowledgments Introduction Endothelial progenitor stavudine (EPCs) circulate in peripheral blood and migrate to a site for vascular formation and repair (Asahara et al., 1997). The pro-angiogenic nature
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The primary determinant of the target specificity of an
2018-11-08
The primary determinant of the target specificity of an individual designer nuclease is the length of its DNA recognition site, which is different in ZFNs, TALENs and the CRISPR/Cas9 system. Also, the GC content substantially influences the target specificity. In theory, a 16bp recognition site shou
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br Acknowledgements br Resource table br Resource details
2018-11-08
Acknowledgements Resource table Resource details To generate the Saudi KACST induced Pluripotent Stem Cell line No 1 (SKiPSc1) cell line, four reprogramming Yamanaka factors (Oct3/4, Sox2, c-Myc, and Klf4) (Takahashi et al., 2007; Yu et al., 2007) were delivered to HNFFs by Sendai viral inf
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br Introduction The grafting of cultured keratinocytes
2018-11-08
Introduction The grafting of cultured keratinocytes to promote regeneration represents one of the oldest clinical examples of stem cell therapy (Green, 2008). The skin constitutes an essential barrier between the living tissues of the body and the external environment, and skin tissues have evolv
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The human GMP was found to yield only neutrophils
2018-11-08
The human GMP was found to yield only neutrophils and not other types of GRs (Görgens et al., 2013). Exactly how monocytes/MΦs and DCs develop downstream of the GMP is intensely studied both in human and mouse. In the mouse, a common monocyte/MΦ/DC progenitor (MDP) has been proposed. The MDP is thou
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Concurrent with the application of gene editing
2018-11-08
Concurrent with the application of gene editing in human cells, the generation of human induced pluripotent stem VX765 manufacturer (iPSCs) was described (Takahashi et al., 2007; Yu et al., 2007). iPSCs possess properties of self-renewal and pluripotency that are similar to those of embryonic stem c
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Numerous morphogenetic events are explained by the
2018-11-08
Numerous morphogenetic events are explained by the cell surface tension model. In equilibrium, surface tension is minimized via coordinated forces generated by cell surface tension and actomyosin-mediated cortical tension, resulting in cell sorting and self-organization (Beysens et al., 2000; Heisen
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The objective of this study was
2018-11-07
The objective of this study was therefore to investigate the prevalence, the effect of SES on prevalence and consequences of work-related physical assaults among people in large Japanese companies using data from the large-scale cross-sectional survey within the Japan Work Stress and Health Cohort S
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br Discussion Research from diverse global contexts confirms
2018-11-07
Discussion Research from diverse global contexts confirms that children born premaritally experience distinct health and developmental challenges compared to children born to married mothers (Singh, 1998). In sub-Saharan Africa, the consequences of being born premaritally are especially severe, i
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