• The ability to generate human vascular endothelium from iPSC

  2018-10-31

  

  The ability to generate human vascular endothelium from iPSCs is an enabling platform. Cell-based assays of endothelial function can be combined with ECs derived from iPSC lines produced from patients with genetic diseases, creating powerful model systems of human disease or associations where the p

• br Human arteriogensis and angiogenesis

  2018-10-31

  

  Human arteriogensis and angiogenesis As in the mouse, the limited human data available strongly support the paradigm that remodeling and pdk1 of pre-existing vascular interconnections (arteriogenesis) is the primary mechanism responsible for providing a new vascular supply in human cardiovascula

• br Resource table Resource details Expanded T

  2018-10-31

  

  Resource table: Resource details Expanded T calcium channel blockers isolated from a 38year-old Japanese healthy male were reprogrammed employing Sendai virus vectors (SeVdp) expressing four reprogramming factors, OCT3/4, SOX2, cMYC, KLF4. SeVdp is integration-free vector, and the absence of re

• Our study extended the doxycycline mediated cell survival ef

  2018-10-31

  

  Our study extended the doxycycline-mediated cell survival effect to human pluripotent ESC/iPSCs. In addition, we show that hESC/iPSC self-renewal is promoted by doxycycline supplementation. Because microglia and inflammatory cells are not present in hESC/iPSC cultures and the doxycycline effects wer

• Introduction Neurotransmitters are critical for nervous syst

  2018-10-31

  

  Introduction Neurotransmitters are critical for nervous system control of behaviors and physiological functions (Kandel et al., 2000; Holz and Fisher, 2012). The challenge in gaining insight into regulation of neurotransmitter secretion in human heme oxygenase disorders has been the lack of human

• We generated an interactive fractal model

  2018-10-31

  

  We generated an interactive fractal model of mammary lobules based on parameters measured in histological sections. The fractal tree can be virtually sectioned at arbitrary depth and angle and then compared to breast tissue sections. This model can quantitate the number of branching generations, the

• The approach for stem cell

  2018-10-31

  

  The approach for stem cell identification utilized herein is functional, based on the relative quiescence and thus label retention property of stem Octreotide acetate within a mixed epithelial population. Long-term 5-bromo-2′-deoxyuridine (BrdU) retention has been previously used to label stem cell

• Lineage instructive TFs act through synergistic and cross an

  2018-10-31

  

  Lineage-instructive TFs act through synergistic and cross-antagonistic interactions, are typically able to access closed chromatin (Zaret and Carroll, 2011), preferentially target sites with specific histone mark combinations, and bind to either nucleosome-depleted or nucleosome-dense regions (Soufi

• Introduction Glioblastoma multiforme GBM is the most

  2018-10-31

  

  Introduction Glioblastoma multiforme (GBM) is the most common adult primary ionomycin tumor, with an extremely dismal prognosis and high rate of recurrence following standard therapy (Wen and Kesari, 2008). Populations of brain tumor initiating cells (BTICs), which express many of the properties o

• In the absence of SOX

  2018-10-31

  

  In the absence of SOX2+ stem cells and Notch signaling in Rbp-Jf/f, Prop1-Cre mutant mice, the pituitary glands are hypoplastic and dysmorphic. Interestingly, re-entry of PIT1+ lineages into the diprenorphine manufacturer after birth is delayed in the mutant. Consistent with our finding, reduced po

• is satisfied where k is the number

  2018-10-30

  

  is satisfied, where k is the number of the least harmonic of the canonical expansion. If we imagine an optimal canonical expansion (7), then k can be set to equal M. The inversely proportional relationship between  T0 and a is in agreement with Kotelnikov’s sampling theorem [11]. Notice that the s

• br Results Table shows the characteristics of the study

  2018-10-30

  

  Results Table 1 shows the characteristics of the study participants by gender. Occupational position differed significantly by gender. Compared to women, men were more likely to be manual/service workers and professionals/managers, and were less likely to be clerks and associate-professionals. Me

• This pattern suggests that we targeted children who

  2018-10-30

  

  This pattern suggests that we targeted children who were already too old to receive maximum benefit from MNP. From Fig. 1 we notice that the studies that found MNP to be most effective at increasing haemoglobin were those with very low average initial haemoglobin (severe anaemia) and where the contr

• Many of the suggested mechanisms by which education may

  2018-10-30

  

  Many of the suggested mechanisms by which education may influence health can be argued to be most strongly operative during secondary schooling, given dramatic cognitive development during adolescence and the emergence of key health issues such as substance use, depression, sexually transmitted infe

• br Tectonomagmatic setting and metallogeny The

  2018-10-30

  

  Tectonomagmatic setting and metallogeny The Hecaokeng uranium ore field is situated approximately 100 km east-southeast of Ganzhou City, southern Jiangxi Province, Southeast China (Fig. 1). It lies in the central part of the Cathaysia Block of Proterozoic age, which is separated from the older Ya

16065 records 1061/1071 page Previous Next First page 上5页 10611062106310641065 下5页 Last page