• However in recent years advanced experiments and findings ar

  2023-12-20

  

  However, in recent years advanced experiments and findings are emerging to give us more detailed information on Aβ-membrane interactions. Several reviews have provided background on the fibrillation of Aβ and the Aβ-membrane interactions [[18], [19], [20], [21], [22]]. In this review, we mainly focu

• The clinical impact of our findings is also

  2023-12-20

  

  The clinical impact of our findings is also supported by our earlier report that the level of 12-LOX expression was correlated with the tumor stage and grade [17], [52] and that overall, 38% of patients demonstrated elevated levels of 12-LOX in prostate cancer tissue compared with their matching nor

• NHS-SS-Biotin Em um estudo com modelos de ratinhos triplamen

  2023-12-20

  

  Em 2011, um estudo com modelos de ratinhos triplamente mutados para NHS-SS-Biotin doença de Alzheimer expôs um grupo a anestesia geral com halotano ou isoflurano cinco horas por semana durante quatro semanas (a três diferentes idades: dois, quatro e seis meses) e um grupo sem exposição aos anestésic

• In our previous study we showed

  2023-12-20

  

  In our previous study we showed that normal and cancerous po1 of kidney exhibit the activity of alcohol dehydrogenase and aldehyde dehydrogenase. Furthermore, the activity of class I ADH isoenzymes and total ADH were significantly higher in cancer tissue than in unchanged renal cells. Moreover, the

• In terms of the full length proteins it was

  2023-12-20

  

  In terms of the full-length proteins, it was noted early on that ACs have two cellular localizations: as integral proteins of the plasma membrane and as soluble proteins in the cytosol. Based on the distribution in mammalian sequences, it was initially proposed that subclass IIIa contains only membr

• In this study we obtained the absorbance and photoluminescen

  2023-12-20

  

  In this study, we obtained the absorbance and photoluminescence (PL) of NU7441 polymerized with various types of actin-binding proteins in order to probe the actin structures in situ without labeling. Both optical measurements have been useful in examining biomaterials such as DNA and proteins with

• br Introduction In myasthenia gravis

  2023-12-20

  

  Introduction In myasthenia gravis (MG), autoantibodies against the native AChR conformation cause loss of AChR at the neuromuscular junction and fatigable muscle weakness (Newsom-Davis et al., 1993). The AChR is a pentameric transmembrane protein, with two splice forms of the α-subunit, P3A− and

• The structures of these compounds were confirmed from

  2023-12-19

  

  The structures of these compounds were confirmed from their spectral and micro analytical data. Based on [M + H] 367, molecular formula of was established as CHON. The IR spectrum of showed rsv due to CO stretching at 1700 Cm & OH stretching at 3188 Cm indicating that compound contains one carbon

• Our results showed suppressed autophagy in

  2023-12-19

  

  Our results showed suppressed autophagy in GECs under HAGG stimulation. Recently, people have paid more attentions on the roles of autophagy in lupus and tried to use autophagy regulators for therapy. Rapamycin could prevent the development of nephritis [49] and attenuate the established nephritis [

• Imatinib is a well known anticancer drug used in Chronic

  2023-12-19

  

  Imatinib is a well-known anticancer drug used in Chronic Myeloid Leukemia (CML) against the altered expression/activity of tyrosine kinase resulting from the fusion of BCR-ABL in leukemic blasts. It has been demonstrated that Imatinib can induce autophagy in BCR-ABL expressing ucf101 (K562 cell lin

• Another contributor for the G M arrest in A and

  2023-12-19

  

  Another contributor for the G2/M arrest in A549 and H1299 cells might be p21WAF1/CIP1 which was up-regulated upon ovatodiolide treatment. p21WAF1/CIP1 is a common CDKs inhibitor which blocks ionomycin G2/M phase progression in various types of cancer cells (Kim et al., 2015, Liberio et al., 2015). I

• ion channel The class C receptors also share a common agonis

  2023-12-19

  

  The class C receptors also share a common agonist-binding mode. In all cases, an agonist induces VFT closure by forming intermolecular bonds with surface residues in both the LB1 and LB2 domains (Geng et al., 2013, Geng et al., 2016, Kunishima et al., 2000, Muto et al., 2007, Nuemket et al., 2017, T

• In vascular endothelial cells L arginine produces

  2023-12-19

  

  In vascular endothelial cells, L-arginine produces nitric oxide (NO) under the action of nitric oxide synthase (NOS), and nitric oxide can activate guanylate cyclase to produce a large amount of cGMP, thereby relaxing vascular smooth muscle and expanding blood vessels. Numerous studies have confirme

• br Discussion br Acknowledgments Writing of this review and

  2023-12-19

  

  Discussion Acknowledgments Writing of this review and collection of data from our laboratories that are presented were supported by a grant from the Belgian Science Policy (BELSPO) SSTC Interuniversity Attraction Poles Plastoscine P7/17 to AVDL and JB, multiple grants from the Fund for Scienti

• Introduction Preeclampsia a serious hypertensive

  2023-12-19

  

  Introduction Preeclampsia, a serious hypertensive disorder that can occur during pregnancy, is a pregnancy-related disease characterized by the onset of UCB 35625 and proteinuria after the 20 t h week of gestation, and it occurs in about 5% of all pregnancies [1]. If left untreated, preeclampsia c

15432 records 183/1029 page Previous Next First page 上5页 181182183184185 下5页 Last page