• br Patients and Methods br

  2023-02-01

  

  Patients and Methods Results Discussion Gjerdrum et al showed that Axl Oleandrin is required to maintain the mesenchymal-like invasiveness of metastatic breast carcinoma cells, but Axl knockdown has no effect on the cell proliferation of MDA-MB-231 cells. Mackiewicz et al also showed that

• In this scenario the receptor tyrosine kinase inhibitors TKI

  2023-02-01

  

  In this scenario, the receptor tyrosine kinase inhibitors (TKI), sunitinib, an anti-angiogenic agent, was tested in phase III trial, leading to a longer progressing free survival when compared to interferon (median: 11 vs. 5mo, respectively, hazard ratio (HR) = 0.42; 95% CI: 0.32–0.54; PMnTBAP Chlor

• Five alternatively spliced isoforms of

  2023-02-01

  

  Five alternatively-spliced isoforms of ATX have been described and all are catalytically active [16], [17]. The original ATX described in 1992 is termed ATXα, whereas the most abundant isoform is ATXβ and is the same isoform responsible for plasma lysoPLD activity [18]. Full length ATX is synthesize

• To maintain ATP levels postmortem muscle mobilizes

  2023-02-01

  

  To maintain ATP levels, postmortem muscle mobilizes its glycogen reserves to yield amyloid definition mg 6-phsphate that proceeds through glycolysis. Glycogen degradation was affected by the interaction between treatment and time (Pinitiation of the experiment. We expected that if myosin ATPase is

• Acknowledgments br Introduction Prostate cancer is

  2023-02-01

  

  Acknowledgments Introduction Prostate cancer is the first leading cause of cancer-related deaths among males in the UK and the second in the US. Despite recent advances in surgery, radiation, medical management and screening, prostate cancer patients suffer high morbidity and mortality and signi

• br Asthma The chronic airway inflammatory

  2023-02-01

  

  Asthma The chronic airway inflammatory disease Cynomolgus ANGPTL7 / Angiopoietin-like 7 Protein (His Tag) is associated with enhanced levels of exhaled NO generated by iNOS in the airway epithelium [12]. In asthmatic patients local and systemic changes in iNOS, peroxynitrite, arginase, ADMA and

• br Androgen interference with the action

  2023-02-01

  

  Androgen interference with the action of arachidonic Epigallocatechin metabolites’ actions; the other side of the coin Arachidonic acid, being a polyunsaturated fatty acid present in the phospholipids of the membrane of cells, is highly abundant within the organism. It is mainly involved in cell

• tnf alpha inhibitor The diversity of metabolic adaptations e

  2023-02-01

  

  The diversity of metabolic adaptations employed by cancer cells in response to rapidly changing conditions, contributes to their biological aggressiveness and therapeutic resistance by enabling them to proliferate when nutrients are plentiful and to shift their resources to survival when nutrients a

• br Results br Discussion By using an

  2023-02-01

  

  Results Discussion By using an unbiased proteomic screen for xCT binding partners, followed by functional validation, we have made the surprising discovery that mTORC2 regulates amino EHop-016 metabolism in tumor cells by phosphorylating serine 26 of the cystine-glutamate antiporter xCT on it

• It is well accepted that PKA is a

  2023-02-01

  

  It is well accepted that PKA is a key enzyme activated at the beginning of the capacitation process [69]. As mentioned above phosphorylation/inactivation of cofilin in sperm is a PKA dependent process [58]. We could not see any change in cofilin phosphorylation level by adding the PKA activator 8Br-

• Although CP has been an important research

  2023-02-01

  

  Although CP has been an important research subject in the field of antigen processing and presentation, the mechanisms of presentation of intracellular O-propargyl-puromycin receptor by MHC II received considerably less attention. Interestingly, pioneering work by the Münz laboratory has pointed to

• There are profound differences between acute

  2023-01-31

  

  There are profound differences between acute and chronic pain when dramatic changes occur in peripheral nociceptors and central nociceptive pathways and the pain system is sensitised thereby leading to exaggerated responses to noxious stimuli (hyperalgesia) and responses to non-noxious stimuli (allo

• MiR has already been implicated in the protective

  2023-01-31

  

  MiR-21 has already been implicated in the protective effects of Res on lung fibrosis, but the molecular mechanisms are underexplored. Our results showed a clear increase of activation protein 1 (AP-1) activity after TGF-β treatment, which was suppressed by Res in a dose-dependent manner, suggesting

• br Antifungal resistance what is in

  2023-01-31

  

  Antifungal resistance, what is in a name? Antifungal resistance is an emerging and hot topic in the field of medical mycology. Microbiological resistance is identified by determining minimal inhibitory concentrations (MICs) in vitro for a given antifungal and interpreting this value according to

• A strain previously reported as

  2023-01-31

  

  A strain previously reported as demonstrating strong antifungal activity and suitability for food applications is Lactobacillus reuteri R29 (Axel et al., 2016, Oliveira et al., 2015). Oliveira et al. (2015) demonstrated that the cell-free supernatant (cfs) of medium fermented for 48 h with this stra

15455 records 311/1031 page Previous Next First page 上5页 311312313314315 下5页 Last page