• The primary cancer lesion was mostly

  2022-03-02

  

  The primary cancer lesion was mostly in the uterus and adnexa, followed by the gastrointestinal tract, brain, blood, and kidney and Creatinine receptor (Fig. 2A). Histopathological findings indicated that most cancers were adenocarcinomas, followed by squamous cell carcinomas, glioblastomas, malign

• DIS used standard methods for locating and contacting person

  2022-03-02

  

  DIS used standard methods for locating and contacting persons for interview, including the use of phone calls, letters, in person contact, and contact through social media. During this time period, contacts of persons with diagnosed HIV (first-generation contacts) were tested for HIV and, regardless

• In this study we evaluated and compared the kinetics

  2022-03-02

  

  In this study we evaluated and compared the kinetics and duration of the oral and systemic HPV-16 and HPV-18 specific antibody response to three doses of the qHPV vaccine in mid-adult aged HIV+ men from the AIDS Malignancy Cohort (AMC) 052 trial and mid-adult aged HIV− men from the Mid-Adult Male [M

• In autoimmune diseases lymphocytes penetrate

  2022-03-02

  

  In autoimmune diseases, lymphocytes penetrate into the inflammatory lesions of tissues, where it is prominently hypoxic or even anoxic, and utilize glycolysis for an energy supply after activation or under hypoxia (Sitkovsky and Lukashev, 2005; Palazon et al., 2014), which is modulated by the oxygen

• GW0742 Mitochondrial binding by HK prevents mortality by inh

  2022-03-02

  

  Mitochondrial binding by HK prevents mortality by inhibiting pro-apoptotic factor (Bcl-2 family)-mediated opening of the mitochondrial permeability transition pore (mPTP) (Arora and Pedersen, 1988, Calmettes et al., 2016, Kodde et al., 2007, Pedersen et al., 2002, Rosano, 2011, Schindler and Foley,

• Overall more males were HCV mono and co infected

  2022-03-01

  

  Overall, more males were HCV mono- and co-infected, though there was no significant age difference among groups and between men and women (all p>0.05). Almost all patients included in this study were over 40 years, in line with the period in which no HCV screening was performed in Brazilian blood b

• CONUT score is an effective detector

  2022-03-01

  

  CONUT score is an effective detector of predicting OS and RFS in HCC patients. We found that patients with a damaged immune-nutrition status had significantly poor OS and RFS. Our initial literature review also retrieved other studies evaluating the survival of HCC patients using CONUT score [36,48,

• In diseased blood vessels increased production of

  2022-03-01

  

  In diseased blood vessels, increased production of reactive oxygen species (ROS), such as peroxynitrite, superoxide, and hydrogen peroxide, have been found [[53], [54], [55]]. Peroxynitrite was suggested to alter the redox state of sGC [53] while hydrogen peroxide interfered with the action of NO bu

• LPC OMe LPC LPC and

  2022-03-01

  

  LPC 14:0, 2-OMe-LPC 14:0, LPC 16:0 and 2-OMe-LPC 16:0 were shown to be most potent stimulators of intracellular calcium flux in the β cell model, which is one of key processes leading to insulin exocytosis. Yet, species with myristoyl residue initiate calcium influx through voltage-gated caspofungin

• thyrotropin receptor Introduction Erythrocyte membrane prote

  2022-02-28

  

  Introduction Erythrocyte membrane proteins or their orthologs are found in almost all thyrotropin receptor of the body [1,2]. Because of this compositional similarity and the erythrocyte membrane's accessibility, the red blood cell membrane (RBCM) has served as a crude model for mammalian plasma m

• br Materials and methods br Conflicts of interest Some of

  2022-02-28

  

  Materials and methods Conflicts of interest Some of the peptidomimetic compounds in this work are the subject of the patent application “Peptidomimetics for Imaging the Ghrelin Receptor”, WO/2016/191865 A1, December 8th, 2016. Acknowledgements Special thanks go to Rebecca McGirr (Lawson He

• br Materials and methods br Results br Discussion Several

  2022-02-28

  

  Materials and methods Results Discussion Several studies highlighted an improvement of glycaemic control in diabetic patients receiving sunitinib, while the underlying mechanism remained still elusive [3], [4], [5], [6], [8]. The present study gives evidence that sunitinib directly and spec

• Although ALPS type is very rare with few published cases

  2022-02-28

  

  Although ALPS type 0 is very rare with few published cases, we herein report the clinical and immunogenetic characteristics of two additional unrelated patients from highly inbred North African population. Both patients present two rare splicing defects mechanisms in FAS gene inducing the skipping o

• In the next set of experiments we sought to determine

  2022-02-28

  

  In the next set of experiments, we sought to determine the source of lysosomal KU14R inhibition by oxidative stress. Lysosomal exocytosis probably involves multiple steps including vesicle positioning, delivery, docking and fusion. The previous evidence and data in Fig. 1C,D show that TRPML1 is cri

• Syringe services programs SSPs as well

  2022-02-28

  

  Syringe services programs (SSPs), as well as expanded HIV and hepatitis C virus (HCV) testing, are key components of harm reduction for PWID and can reduce HIV and hepatitis C virus (HCV) transmissions in this hydroxychloroquine sulfate [14], [15], [16]. The number of SSPs has increased in recent y

16071 records 486/1072 page Previous Next First page 上5页 486487488489490 下5页 Last page