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Heat shock facilitates the folding of various proteins as
2019-06-10
Heat shock facilitates the folding of various proteins as mediated by the HSP family and can stabilize mutant proteins. HS has been reported to facilitate maturation of WT-HERG as well as mutant HERG by activating the HSF family [15]. HSF-1, 2, and 4 were reported to be expressed in humans. HSF-1 is
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Infectious and parasitic diseases cause
2019-06-10
Infectious and parasitic diseases cause about half the anaemia burden. Stevens and colleagues estimate that iron-amenable anaemia was about 50% in non-pregnant and pregnant women, and 42% in children in 2011. In addition to the contributions of malaria, schistosomiasis, hookworm infection, and HIV,
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br Discussion Intriguingly in a case report about elevation
2019-06-10
Discussion Intriguingly, in a case report about elevation of skeletal enzymes in ultramarathon runners, the CK level reached its peak value one day after the run, had a ∼4-day plateau, and began to decline after a few more days. The sustained increase of plasma CK in this athlete was quite differ
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br Conflict of interest br Ethics
2019-06-10
Conflict of interest Ethics Acknowledgment This study was supported by TRF Grants from the Senior Research Scholar Grant, Thailand Research Fund Grant number RTA5580004, and the Higher Education Research Promotion and National Research University Project of Thailand, Office of the Higher Ed
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The OptiVol Fluid Index OVFI which is derived from changes
2019-06-06
The OptiVol Fluid Index (OVFI), which is derived from changes in intrathoracic impedance, can effectively assess HF by analyzing the changes in the intrathoracic impedance detected by the original OptiVol algorithm. Small et al. previously determined that a frequent and extended threshold crossing B
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The renin angiotensin system plays a crucial role in
2019-06-06
The renin-angiotensin system plays a crucial role in atrial fibrosis, which is a key pathological consequence of AF. Genes encoding 3 molecules related to the renin-angiotensin system, including angiotensin-converting enzyme (ACE), angiotensinogen, and angiotensin type 1 receptor (AT1R), are associa
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Univariate analysis for overall survival revealed
2019-06-06
Univariate analysis for overall survival revealed that age (≤, >50 years), menopausal status, T-N stage, and histological tumor size were statistically significant factors for survival. Menopausal status was determined after two years of amenorrhea. In post-menopausal women, the disease-free surviva
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Introduction Hepatosplenic T cell lymphoma HSTCL is a
2019-06-06
Introduction Hepatosplenic T-cell lymphoma (HSTCL) is a rare subtype of peripheral T-cell lymphoma, which is derived from cytotoxic T-cells typically expressing γδ T-cell receptor (TCR). It usually occurs in young men and is characterized by B symptoms such as a fever, weight loss and night sweats,
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In Rachel Lowe and colleagues show the potential of
2019-06-06
In , Rachel Lowe and colleagues show the potential of application of climate services for health to dengue in the city of Machala, El Oro Province, Ecuador, where dengue is hyperendemic and transmitted throughout the year with co-circulation of all four dengue serotypes. Machala is an ideal site for
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In Jillian Pintye and colleagues from the Partners
2019-06-06
In Jillian Pintye and colleagues from the Partners PrEP study team present one of the largest and most comprehensive analyses of syphilis incidence in men and women and the effect of male circumcision. The investigators followed 4716 HIV-1 serodiscordant couples, of whom roughly 50% of the men were
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Importa notar al mismo tiempo cierta impaciencia
2019-06-06
Importa notar, al mismo tiempo, cierta impaciencia con la indeterminación del saber celebrada hasta no hace mucho. En la ruta hacia el neoliberalismo, ese tránsito del Estado al mercado —como suele llamársele en América Latina—, la duda epistémica, el pensamiento débil, los juegos de lenguaje y la r
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br Consideracj es fin is
2019-06-06
Consideracjóes fináis De acordo com as evidências coletadas com adiponectin receptor pesquisa, algumas discussões passam a ser sugeridas. Inicialmente, das parcerias entre Estado e sociedade foram abertas vagas na saúde públicas a serem ocupadas por “pessoas jurídicas de direito privados”, e mesm
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Desde la perspectiva expuesta la etnicidad constituye
2019-06-06
Desde la perspectiva expuesta, la etnicidad constituye una dimensión potencial de la identidad, fundamentada en un conjunto de elementos que, al seguir la tradición weberiana, pueden abarcar la percepción de origen, cultura, idioma o rasgos fenotípicos compartidos por un conjunto de personas. La adq
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En Latinoam rica donde se presentan intentos
2019-06-06
En Latinoamérica, donde se presentan intentos de fundar identidades regionales o nacionales que ejerzan contrapeso abnormal lipid metabolism los embates de homogeneización cultural, han aparecido diversos criterios relacionados con políticas universalistas o con el cosmopolitismo. Estos criterios su
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Chronic myelogenous leukemia blast crisis is highly refracto
2019-06-06
Chronic myelogenous leukemia blast crisis is highly refractory to standard induction chemotherapy, with a response rate of less than 20–30% [12,13]. In patient\'s with Imatinib resistant disease Dastanib and Nilotinib can help achieve hematological response however neither drug has been reported to
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