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Furthermore as much as nutritional well being is
2018-10-24
Furthermore, as much as nutritional well-being is determined by genetic predisposition and individual behaviour, it is also a matter of social justice. While the effects of inequality may appear relatively minor, they affect millions of Indonesians. An economic policy that promotes equity and qualit
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The results in Table show that for the total sample
2018-10-24
The results in Table 3 show that, for the total sample, the education coefficient is reduced by 10% in the binary component and 23% in the conditional component with the inclusion of the occupational categories. Models 4 and 5 in Table 2 present the analogous models with controls for wealth instead
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In these issues of Lan and colleagues describe
2018-10-23
In these issues of , Lan and colleagues describe vaccine studies in a non-human primate model of MERS-CoV infection (). Building on previous studies in rhesus macaques with SARS-CoV (), the report details the efficacy of a MERS vaccine based on a recombinant bch binding domain (RBD) subunit. Their
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One case control study and several
2018-10-23
One case–control study and several case reports, including a total of 7 patients, suggested an association between linezolid mitochondrial toxicity and the mitochondrial ribosomal RNA polymorphisms A2706G or G3010A (Palenzuela et al., 2005; Carson et al., 2007; Velez and Janech, 2010; Del Pozo et al
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In this issue of report a study which used
2018-10-23
In this issue of , report a study which used the publicly available data from the American Gut Project including questionnaires and fecal 16S rRNA sequence data. The report focuses on associations between self-reported allergies and the adult fecal microbiota composition. Self-reported allergy prev
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While the precise biological mechanisms by
2018-10-23
While the precise biological mechanisms by which obesity and weight loss affect cognitive function are unclear, several plausible pathways exist, including oxidative stress, inflammation, metabolic impairments and vascular dysfunction (Bruce-Keller et al., 2009). Of these potential mechanisms, cereb
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Understanding how barrier tissues function
2018-10-23
Understanding how barrier tissues function is essential for the design of effective pharmaceutical compounds. Once these devices are transitioned from research to clinical use, and we have more accurate predictive models early on in the development process, we will likely see an end to the recent st
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Membrane disruption and ion dysregulation are known componen
2018-10-23
Membrane disruption and ion dysregulation are known components of Aβ toxicity. Aβ oligomers have also been shown to directly interact with membranes forming pores and disrupting the proper permeability of membranes (Kayed and Lasagna-Reeves, 2013). A distinct pore structured oligomer termed an annul
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br Size Stability and Toxicity A substantial
2018-10-23
Size, Stability, and Toxicity A substantial number of investigations aiming to unravel the mechanism of the disease have accepted an intermediate structure of aggregated Aβ which is formed earlier than plaques and has been linked to the pathogenesis (Kayed and Lasagna-Reeves, 2013; Klein, 2013; H
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The US Department of Agriculture USDA
2018-10-23
The US Department of Agriculture (USDA) and US Department of Health and Human Services recommend 2 cups (3–4 servings (U.S. Department of Health and Human Services and U.S. Department of Agriculture, 2000)) of p2x7 per day for active women. One cup of fruit (U.S. Department of Health and Human Serv
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br Funding br Conflict of Interest
2018-10-23
Funding Conflict of Interest Statement Author Contributions Acknowledgements This work was supported in part by the University of Zurich, Switzerland, and the Federal Office of Public Health, Switzerland. Introduction Conformational diseases, which include Alzheimer\'s disease and
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In contrast we observed no evidence that changes
2018-10-23
In contrast, we observed no evidence that changes in PCC/precuneus-pons rs-FC predicted changes in affective ratings among the relaxation group. Two reasons might explain why we specifically found the association in the meditation group. First, previous evidence that meditation training influences P
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Interestingly SR had an anabolic effect on the appendicular
2018-10-23
Interestingly, SR10171 had an anabolic effect on the appendicular but not the axial skeleton, whereas rosiglitazone had a negative effect in both skeletal sites. There are several possible explanations for this divergence. Firstly, osteocytes were shown to be a major anabolic target of SR10171. Thes
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br Methods br Discussion We systematically searched the
2018-10-23
Methods Discussion We systematically searched the literature from the last five years to identify potential blood biomarkers for cancer (Hanahan & Weinberg, 2011; Cree, 2011). The data mining process retrieved 3990 citations from the initial 19, 724 records, screening the abstracts of these ci
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It should be pointed out that the study reported
2018-10-23
It should be pointed out that the study reported here has been conducted with a segment of ClfA and it is unclear if Fg binding to the full-length MSCRAMM can involve even more extensive interactions outside the N2N3 sub-domains. Our studies with tefibazumab have also revealed a novel inhibitory mec
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